TP54

TP0463518
HY-112144 10mg
EUR 270.57
Description: TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with a Ki value of 5.3 nM for human PHD2. TP0463518 also inhibits human PHD1/PHD3 with IC50s of 18 and 63 nM as well as monkey PHD2 with an IC50 value of 22 nM[1].
TP0480066
HY-150045 Get quote Ask for price
Description: TP0480066 is a selective topoisomerase II inhibitor with IC50s of 1.10 and 62.89 nM for DNA gyrase and topo IV, respectively. TP0480066 shows good activity of againsting various bacterial species including drug-resistant strains. TP0480066 also exhibits potent inhibitory activity to N. gonorrhoeae, can be used in study of gonorrhea[1][2].
TP0472993
HY-151810 10 mg
EUR 714.3
Description: CYP4A11/CYP4F2-IN-2 is a potent and orally active dual inhibitor of cytochrome P450 (CYP) 4A11 and CYP4F2, with IC50s of 140 nM and 40 nM, respectively. CYP4A11/CYP4F2-IN-2 has potential for the research of renal diseases[1].
TP0628103
HY-161169 Get quote Ask for price
Description: TP0628103 (compound 18) is a selective inhibitor of MMP-7, with the IC50 value of 0.17 nM that plays an important role in cancer and fibrosis[1].
TP0586532
HY-131981 10 mg
EUR 1948.08
Description: TP0586532 is a non-hydroxamate LpxC inhibitor (IC50=0.101 μM). TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains[1]. TP0586532 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
TP0427736
HY-118528 Get quote Ask for price
Description: TP0427736 is a selective inhibitor of ALK5 with an IC50 of 2.72 nM. TP0427736 inhibits Smad2/3 phosphorylation in A549 cells. TP0427736 decreases the growth inhibition of human outer root sheath cells[1].
TP0556351
HY-147936 Get quote Ask for price
Description: TP0556351 is a potent and selective matrix metalloproteinase-2 (MMP2) inhibitor with an IC50 value of 0.2 nM. TP0556351 reduces the amount of collagen in the lungs of a Bleomycin-induced pulmonary fibrosis mouse model. TP0556351 can be used for researching idiopathic pulmonary fibrosis (IPF)[1].
TP0597850
HY-148571 10 mg
EUR 3463.26
Description: TP0597850 is a selective inhibitor of MMP2 (IC50=0.22 nM). TP0597850 has a long MMP2 dissociation half-life (t1/2=265 min)[1].
TP0586352
HY-142619 Get quote Ask for price
Description: TP0586352 is a LpxC inhibitor that is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk. TP0586352 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
TP-0463518
MBS3602216-10mg 10mg
EUR 735
TP-0463518
MBS3602216-5mg 5mg
EUR 495
TP-0463518
MBS3602216-5x10mg 5x10mg
EUR 2980
TP0463518
MBS3844632-10mg 10mg
EUR 870
TP0463518
MBS3844632-50mg 50mg
EUR 2485
TP0463518
MBS3844632-5mg 5mg
EUR 545
TP0463518
MBS3844632-5x50mg 5x50mg
EUR 11175
TP0463518
MBS5751803-100mg 100mg
EUR 420
TP0463518
MBS5751803-10mg 10mg
EUR 170
TP0463518
MBS5751803-25mg 25mg
EUR 210
TP0463518
MBS5751803-50mg 50mg
EUR 275
TP0463518
MBS5751803-5mg 5mg
EUR 150
TP0427736
MBS5774637-10mg 10(mg
EUR 420
TP0427736
MBS5774637-1mg 1(mg
EUR 210
TP0427736
MBS5774637-5mg 5(mg
EUR 315
TP0586532
MBS5786232-10mg 10(mg
EUR 545
TP0586532
MBS5786232-1mg 1(mg
EUR 235
TP0586532
MBS5786232-5mg 5(mg
EUR 375
TP0586352
MBS5800398-5mg 5(mg
EUR 915
TP0586352
MBS5800398-5x5mg 5x5(mg
EUR 3970
TP0463518
T5392-10mg 10mg Ask for price
Description: TP0463518
TP0463518
T5392-1g 1g Ask for price
Description: TP0463518
TP0463518
T5392-1mg 1mg Ask for price
Description: TP0463518
TP0463518
T5392-50mg 50mg Ask for price
Description: TP0463518
TP0463518
T5392-5mg 5mg Ask for price
Description: TP0463518
TP0427736
T24897-10mg 10mg Ask for price
Description: TP0427736
TP0427736
T24897-1g 1g Ask for price
Description: TP0427736
TP0427736
T24897-1mg 1mg Ask for price
Description: TP0427736
TP0427736
T24897-50mg 50mg Ask for price
Description: TP0427736
TP0427736
T24897-5mg 5mg Ask for price
Description: TP0427736
TP0586352
T40088-10mg 10mg Ask for price
Description: TP0586352
TP0586352
T40088-1g 1g Ask for price
Description: TP0586352
TP0586352
T40088-1mg 1mg Ask for price
Description: TP0586352
TP0586352
T40088-50mg 50mg Ask for price
Description: TP0586352
TP0586352
T40088-5mg 5mg Ask for price
Description: TP0586352
TP0480066
T61481-10mg 10mg Ask for price
Description: TP0480066
TP0480066
T61481-1g 1g Ask for price
Description: TP0480066
TP0480066
T61481-1mg 1mg Ask for price
Description: TP0480066
TP0480066
T61481-50mg 50mg Ask for price
Description: TP0480066
TP0480066
T61481-5mg 5mg Ask for price
Description: TP0480066
TP0586532
T9318-10mg 10mg Ask for price
Description: TP0586532
TP0586532
T9318-1g 1g Ask for price
Description: TP0586532
TP0586532
T9318-1mg 1mg Ask for price
Description: TP0586532
TP0586532
T9318-50mg 50mg Ask for price
Description: TP0586532
TP0586532
T9318-5mg 5mg Ask for price
Description: TP0586532
TP0427736 (hydrochloride)
HY-118528A 10 mg
EUR 1109.32
Description: TP0427736 hydrochloride is a potent inhibitor of ALK5 kinase activity with an IC50 of 2.72 nM and this effect is 300-fold higher than the inhibitory effect on ALK3 (IC50=836 nM). TP0427736 hydrochloride also inhibits Smad2/3 phosphorylation in A549 cells induced by TGF-β1 with an IC50 value of 8.68 nM. TP0427736 hydrochloride can be used for the research of androgenic alopecia (AGA)[1].
TP0427736 hydrochloride
T61029-10mg 10mg Ask for price
Description: TP0427736 hydrochloride
TP0427736 hydrochloride
T61029-1g 1g Ask for price
Description: TP0427736 hydrochloride
TP0427736 hydrochloride
T61029-1mg 1mg Ask for price
Description: TP0427736 hydrochloride
TP0427736 hydrochloride
T61029-50mg 50mg Ask for price
Description: TP0427736 hydrochloride
TP0427736 hydrochloride
T61029-5mg 5mg Ask for price
Description: TP0427736 hydrochloride
TP-2857
555613 50.0mg
EUR 450
TP-4748
555631 100.0mg Ask for price
TP-3654
527505 5.0mg
EUR 150
TP-0903
9590-25 each
EUR 705.6
TP-0903
9590-5 each
EUR 235.2
TP-3654
B2229-5 each
EUR 210
TP-0903
B5940-10 10 mg
EUR 120
Description: Tyrosine Kinase|Axl
TP-0903
B5940-100 100 mg
EUR 520
Description: Tyrosine Kinase|Axl
TP-0903
B5940-5 5 mg
EUR 64
Description: Tyrosine Kinase|Axl
TP-0903
B5940-50 50 mg
EUR 360
Description: Tyrosine Kinase|Axl
TP-0903
MBS130719-100mg 100mg
EUR 1065
TP-0903
MBS130719-500mg 500mg
EUR 2775
TP-3654
MBS131882-INQUIRE INQUIRE Ask for price
TP-1287
HY-153260 1 mg
EUR 2770.61
Description: TP-1287, a prodrug of Alvocidib (HY-10005), is an orally active CDK9 inhibitor[1].
TP3011
HY-135845 Get quote Ask for price
Description: TP3011 (CH0793011) is an active metabolite of CH-0793076 and is a potent topoisomerase I inhibitor equipotent as SN38[1]. TP3011 is against cancer cell lines growth with IC50s at the range sub-nanomolar in vitro[2].
TP-3654
HY-101126 10mM/1mL
EUR 333.34
Description: TP-3654 is a second-generation Pim kinase inhibitor with Ki values of 5 and 42 nM for Pim-1 and Pim-3, respectively.