Bovine serum albumin/chitosan-nanoparticle bio-complex; spectroscopic study and in vivo toxicological – Hypersensitivity evaluation

This study, investigates the interplay of bovine serum albumin (BSA) with synthesized chitosan nanoparticles (CSNPs) utilizing regular-state fluorescence and UV-vis absorbance spectroscopy in addition to picosecond time-resolved fluorescence approach. The fluorescence quenching mechanism of BSA by CSNPs signifies the presence of each static and dynamic mechanism.
The loading effectivity of BSA-CSNPs exhibited a lower by about 6% in impartial pH underneath physiological temperature. Transmission electron microcopy (TEM) photographs revealed the Synthesized CSNPs have been irregular in form with measurement of ~42 nm.
The security and biocompatibility of BSA-CSNPs contained in the physique was investigated after intraperitoneal (IP) injection of male mice for 9 days, evaluation of in vivo outcomes, revealed no toxicity with a hypocholesterolemic impact and a predicted gentle activation of WBCs as a result of CSNPs adjuvant and immunogenic peptides in BSA. Accordingly, no indicators of hypersensitivity have been noticed as a result of administration of such formulations. The outcomes can be utilized for a greater understanding the interplay of CSNPs inside organic protein setting.

Development of a LC-MS/MS methodology to measure serum 3-sulfate and 3-glucuronide 25-hydroxyvitamin D3 metabolites; comparisons to unconjugated 25OHD in being pregnant and polycystic ovary syndrome

Vitamin D standing is routinely assessed by measuring circulating concentrations of 25-hydroxyvitamin D (25OHD2 or 25OHD3). However as deconjugation isn’t routinely integrated into pattern remedy previous to evaluation, conjugated types of 25OHD (significantly the extra plentiful 25OHD3) are sometimes not thought of in figuring out serum concentrations of complete 25OHD.
Two main circulating conjugated types of 25OHD3 are 25-hydroxyvitamin D3-3-sulfate (25OHD3-S) and 25-hydroxyvitamin D3-3-glucuronide (25OHD3-G). Incorporating these two conjugated metabolites into the measurement of vitamin D standing may enhance our understanding of vitamin D standing in well being, significantly if there are modifications in sulfation and glucuronidation actions.
The purpose of this study was to develop a liquid chromatography tandem-mass spectrometry (LC-MS/MS) focused methodology for measurement of 25OHD3-S and 25OHD3-G in serum to allow comparisons with circulating ranges of the free 25OHD3 type. We developed and validated a brand new LC-MS/MS methodology that measured each 25OHD3-S and 25OHD3-G following a strong section extraction pattern preparation methodology.
Partial separation of analytes by LC, and the separation of analytes by the optimized a number of response monitoring transitions enabled the quantitation of each 25OHD3-S and 25OHD3-G in the one methodology. Serum concentrations of 25OHD3-S (24.7 ± 11.eight ng/mL) and 25OHD3-G (2.4 ± 1.2 ng/mL) have been proven to be a major proportion of circulating vitamin D metabolites in wholesome donor serums. These ranges of 25OHD3-S and 25OHD3-G intently related to 25OHD3 concentrations, r=0.728, p=0.001 and r=0.632, p=0.006 respectively.
However in serum from pregnant ladies and non-pregnant ladies with polycystic ovary syndrome (PCOS) vital variations in the ratios between conjugated and free 25OHD3 have been noticed between being pregnant teams (25OHD3/25OHD3-S and 25OHD3/25OHD3-G p<0.001), and between wholesome and PCOS topics (25OHD3/25OHD3-G p<0.050).
Development of this novel excessive-throughput LC-MS/MS methodology signifies that 25OHD3-S and 25OHD3-G are substantial parts of circulating vitamin D metabolites. The concentrations of those metabolites relative to standard 25OHD3 could fluctuate in completely different physiological and pathophysiological settings, and could subsequently play an unrecognized however vital function in the actions of vitamin D.

Low serum levels of cholesterol predict inferior prognosis and enhance prognostic index scoring for peripheral T-cell lymphoma, unspecified

Peripheral T-cell lymphomas, unspecified (PTCL-U) is a heterogeneous group of non-Hodgkin lymphomas, arising from the transformation of mature, put up-thymic T-cells. Prognostic index for PTCL-U (PIT) is predicated on Europeans and might not be relevant for Chinese PTCL-U sufferers. Besides, low circulating ldl cholesterol focus is related to elevated most cancers incidence and mortality.
The objective of our study was to evaluate the prognostic worth of serum lipid ranges in PTCL-U and enhance PIT. We screened the prognostic elements related to development-free survival (PFS) and general survival (OS) by multivariate Cox regression evaluation in ninety-one enrolled sufferers. The outcomes confirmed that low-stage excessive-density lipoprotein ldl cholesterol (HDL-C) and low-density lipoprotein ldl cholesterol (LDL-C) have been related to unfavorable OS. Furthermore, we developed a brand new danger mannequin, PITC, based mostly on low-stage HDL-C, LDL-C and PIT. In Chinese PTCL-U, PITC was superior to PIT in PFS and OS. In conclusion, serum levels of cholesterol could also be good candidates for predicting prognosis in PTCL-U.

Profiling of Serum Exosome MiRNA Reveals the Potential of a MiRNA Panel as Diagnostic Biomarker for Alzheimer’s Disease

Alzheimer’s illness (AD) is the most typical neurodegenerative illness in the older adults. Although a lot effort has been made in the analyses of diagnostic biomarkers, reminiscent of amyloid-β, tau, and neurofilament mild chain, figuring out peripheral blood-based mostly biomarkers is in extraordinarily pressing want for his or her minimal invasiveness and extra comfort.
Bovine serum albumin/chitosan-nanoparticle bio-complex; spectroscopic study and in vivo toxicological - Hypersensitivity evaluation
Here we characterised the miRNA profile by RNA sequencing in human serum exosomes from AD sufferers and wholesome controls (HC) to analyze its potential for AD analysis. Subsequently, Gene Ontology evaluation and pathway evaluation have been carried out for the focused genes from the differentially expressed miRNAs. These fundamental capabilities have been differentially enriched, together with cell adhesion, regulation of transcription, and the ubiquitin system.
Functional community evaluation highlighted the pathways of proteoglycans in most cancers, viral carcinogenesis, signaling pathways regulating pluripotency of stem cells, and mobile senescence in AD. A complete of 24 miRNAs confirmed considerably differential expression between AD and HC with greater than ± 2.0-fold change at p worth < 0.05 and at the very least 50 reads for every pattern. Logistic regression evaluation established a mannequin for AD prediction by serum exosomal miR-30b-5p, miR-22-3p, and miR-378a-3p.

EZ-DNA Reagents

SK8201 100preps
EUR 93.5

EZ-DNA Reagents

BS8202 100preps
EUR 88.06

Human Free PSA (f-PSA) ELISA Kit

PRB-5049-FREE-5 5 x 96 assays
EUR 2283

Bovine Serum Albumin, protease free

GK4012-1KG 1 kg
EUR 971

Bovine Serum Albumin, protease free

GK4012-500G 500 g
EUR 532

PK15 Cell Serum-Free Medium

VCum-Lsx0007 1 L
EUR 758
Description: PK15 cell serum-free medium has been specifically developed for suspension culture of PK-15 cells.

CHO Cell Serum-Free Medium

VCum-Lsx0025 1L
EUR 635
Description: A serum-free medium that is ideal for suspension culture of CHO cell lines (CHO DG44, CHO-K1 and CHO-S).

HEK Cell Serum-Free Medium

VCum-Lsx0027 1L
EUR 635
Description: A serum-free medium that is ideal for suspension culture of HEK cell lines.

MDBK Cell Serum-Free Medium

VCum-Lsx0029 1L
EUR 682
Description: Used in serum-free suspension MDBK cell line culture for bovine virus diarrhea or bovine rhinotracheitis vaccine production.

Vero Cell Serum-Free Medium

VCum-Lsx0031 1 L
EUR 758
Description: A serum-free medium that is ideal for suspension culture of Vero cell lines.

Serum Albumin, Lipid Free Protein

20-abx260049
  • EUR 773.00
  • EUR 286.00
  • EUR 523.00
  • 100 mg
  • 10 mg
  • 50 mg

Human Serum (Troponin I Free)

90R-106 100 ml
EUR 1181
Description: Troponion I free normal human serum

Fetal Bovine Serum, Premium Tetracyclin Free

F0500-050 500ml
EUR 1157

Bovine Serum Albumin, fatty acid free

GX5685-1KG 1 kg
EUR 1202

Bovine Serum Albumin, fatty acid free

GX5685-500G 500 g
EUR 660

ST Cell Serum-Free Medium-1

VCum-Lsx0001 1 L
EUR 740
Description: ST cell serum-free medium has been specifically developed for suspension culture of ST cells.

ST Cell Serum-Free Medium-2

VCum-Lsx0003 1 L
EUR 758
Description: ST cell serum-free medium has been specifically developed for suspension culture of ST cells.

PK15 Cell Serum-Free Medium (Powder)

VCum-Lsx0008-10L 10 L
EUR 2332
Description: PK15 cell serum-free medium has been specifically developed for suspension culture of PK-15 cells.

PK15 Cell Serum-Free Medium (Powder)

VCum-Lsx0008-1L 1 L
EUR 278
Description: PK15 cell serum-free medium has been specifically developed for suspension culture of PK-15 cells.

PK15 Cell Serum-Free Medium (Powder)

VCum-Lsx0008-5L 5 L
EUR 1191
Description: PK15 cell serum-free medium has been specifically developed for suspension culture of PK-15 cells.

MDCK Cell Serum-Free Medium-1

VCum-Lsx0009 1 L
EUR 682
Description: MDCK cell serum-free medium has been specifically developed for suspension culture of MDCK cells.

MDCK Cell Serum-Free Medium-2

VCum-Lsx0011 1 L
EUR 694
Description: Used in serum-free suspension MDCK cell line culture for avian influenza vaccine production.

BHK Cell Serum-Free Medium-1

VCum-Lsx0017 1 L
EUR 647
Description: BHK cell serum-free medium has been specifically developed for suspension culture of BHK cells.

BHK Cell Serum-Free Medium-2

VCum-Lsx0019 1 L
EUR 717
Description: Used in serum-free suspension BHK cell line culture for newcastle disease virus production.

Insect Cell Serum-Free Medium-1

VCum-Lsx0021 1 L
EUR 740
Description: A serum-free medium that is ideal for suspension culture of insect cell lines (HighFive, SF9).

Insect Cell Serum-Free Medium-2

VCum-Lsx0023 1 L
EUR 758
Description: A serum-free medium that is ideal for suspension culture of insect cell lines (HighFive, SF9).

CHO Cell Serum-Free Medium (Powder)

VCum-Lsx0026-10L 10 L
EUR 1747
Description: A serum-free medium that is ideal for suspension culture of CHO cell lines (CHO DG44, CHO-K1 and CHO-S).

CHO Cell Serum-Free Medium (Powder)

VCum-Lsx0026-1L 1 L
EUR 220
Description: A serum-free medium that is ideal for suspension culture of CHO cell lines (CHO DG44, CHO-K1 and CHO-S).

CHO Cell Serum-Free Medium (Powder)

VCum-Lsx0026-5L 5 L
EUR 898
Description: A serum-free medium that is ideal for suspension culture of CHO cell lines (CHO DG44, CHO-K1 and CHO-S).

HEK Cell Serum-Free Medium (Powder)

VCum-Lsx0028 50 L
EUR 6411
Description: A serum-free medium that is ideal for suspension culture of HEK cell lines.

MDBK Cell Serum-Free Medium (Powder)

VCum-Lsx0030 50 L
EUR 8591
Description: Used in serum-free suspension MDBK cell line culture for bovine virus diarrhea or bovine rhinotracheitis vaccine production.

Vero Cell Serum-Free Medium (Powder)

VCum-Lsx0032-10L 10 L
EUR 2332
Description: A serum-free medium that is ideal for suspension culture of Vero cell lines.

Vero Cell Serum-Free Medium (Powder)

VCum-Lsx0032-1L 1 L
EUR 282
Description: A serum-free medium that is ideal for suspension culture of Vero cell lines.

Vero Cell Serum-Free Medium (Powder)

VCum-Lsx0032-5L 5 L
EUR 1208
Description: A serum-free medium that is ideal for suspension culture of Vero cell lines.

B-27 Serum-Free Supplement (50x)

abx082466-10ml 10 ml
EUR 328

CORNING® LYMPHOCYTE SERUM FREE MEDIUM

88-551-CM 1/pk
EUR 149
Description: Specialty Media; Kohjin Products

CORNING® LYMPHOCYTE SERUM FREE MEDIUM

88-581-CM 1/pk
EUR 189
Description: Specialty Media; Kohjin Products

Normal Bovine Serum (Protease/IgG free)

88R-1012 10 ml
EUR 182
Description: Normal Bovine Serum which has been lipid extracted and dialyzed against 10 mM Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Set of 10 Biolipidure Reagents

Biolipidure-set 10mLx10
EUR 1517
Description: Set of 10 Biolipidure Reagents, whose applications include Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

ST Cell Serum-Free Medium-1 (Powder)

VCum-Lsx0002-10L 10 L
EUR 2215
Description: ST cell serum-free medium has been specifically developed for suspension culture of ST cells.

ST Cell Serum-Free Medium-1 (Powder)

VCum-Lsx0002-1L 1 L
EUR 266
Description: ST cell serum-free medium has been specifically developed for suspension culture of ST cells.

ST Cell Serum-Free Medium-1 (Powder)

VCum-Lsx0002-5L 5 L
EUR 1132
Description: ST cell serum-free medium has been specifically developed for suspension culture of ST cells.

ST Cell Serum-Free Medium-2 (Powder)

VCum-Lsx0004-10L 10 L
EUR 2332
Description: ST cell serum-free medium has been specifically developed for suspension culture of ST cells.

ST Cell Serum-Free Medium-2 (Powder)

VCum-Lsx0004-1L 1 L
EUR 278
Description: ST cell serum-free medium has been specifically developed for suspension culture of ST cells.

ST Cell Serum-Free Medium-2 (Powder)

VCum-Lsx0004-5L 5 L
EUR 1191
Description: ST cell serum-free medium has been specifically developed for suspension culture of ST cells.

MDCK Cell Serum-Free Medium-1 (Powder)

VCum-Lsx0010-10L 10 L
EUR 1864
Description: MDCK cell serum-free medium has been specifically developed for suspension culture of MDCK cells.

MDCK Cell Serum-Free Medium-1 (Powder)

VCum-Lsx0010-1L 1 L
EUR 231
Description: MDCK cell serum-free medium has been specifically developed for suspension culture of MDCK cells.

MDCK Cell Serum-Free Medium-1 (Powder)

VCum-Lsx0010-5L 5 L
EUR 957
Description: MDCK cell serum-free medium has been specifically developed for suspension culture of MDCK cells.

MDCK Cell Serum-Free Medium-2 (Powder)

VCum-Lsx0012-10L 10 L
EUR 1922
Description: Used in serum-free suspension MDCK cell line culture for avian influenza vaccine production.

MDCK Cell Serum-Free Medium-2 (Powder)

VCum-Lsx0012-1L 1 L
EUR 237
Description: Used in serum-free suspension MDCK cell line culture for avian influenza vaccine production.

MDCK Cell Serum-Free Medium-2 (Powder)

VCum-Lsx0012-5L 5 L
EUR 986
Description: Used in serum-free suspension MDCK cell line culture for avian influenza vaccine production.

BHK Cell Serum-Free Medium-1 (Powder)

VCum-Lsx0018-10L 10 L
EUR 1688
Description: BHK cellserum-free medium has been specifically developed for suspension culture of BHK cells.

BHK Cell Serum-Free Medium-1 (Powder)

VCum-Lsx0018-1L 1 L
EUR 214
Description: BHK cellserum-free medium has been specifically developed for suspension culture of BHK cells.

BHK Cell Serum-Free Medium-1 (Powder)

VCum-Lsx0018-5L 5 L
EUR 869
Description: BHK cellserum-free medium has been specifically developed for suspension culture of BHK cells.

BHK Cell Serum-Free Medium-2 (Powder)

VCum-Lsx0020-10L 10 L
EUR 1922
Description: Used in serum-free suspension BHK cell line culture for newcastle disease virus production.

BHK Cell Serum-Free Medium-2 (Powder)

VCum-Lsx0020-1L 1 L
EUR 237
Description: Used in serum-free suspension BHK cell line culture for newcastle disease virus production.

BHK Cell Serum-Free Medium-2 (Powder)

VCum-Lsx0020-5L 5 L
EUR 986
Description: Used in serum-free suspension BHK cell line culture for newcastle disease virus production.

Insect Cell Serum-Free Medium-1 (Powder)

VCum-Lsx0022-10L 10 L
EUR 2215
Description: A serum-free medium that is ideal for suspension culture of insect cell lines (HighFive, SF9).

Insect Cell Serum-Free Medium-1 (Powder)

VCum-Lsx0022-1L 1 L
EUR 266
Description: A serum-free medium that is ideal for suspension culture of insect cell lines (HighFive, SF9).

Insect Cell Serum-Free Medium-1 (Powder)

VCum-Lsx0022-5L 5 L
EUR 1132
Description: A serum-free medium that is ideal for suspension culture of insect cell lines (HighFive, SF9).

Insect Cell Serum-Free Medium-2 (Powder)

VCum-Lsx0024-10L 10 L
EUR 2332
Description: A serum-free medium that is ideal for suspension culture of insect cell lines (HighFive, SF9).

Insect Cell Serum-Free Medium-2 (Powder)

VCum-Lsx0024-1L 1 L
EUR 278
Description: A serum-free medium that is ideal for suspension culture of insect cell lines (HighFive, SF9).

Insect Cell Serum-Free Medium-2 (Powder)

VCum-Lsx0024-5L 5 L
EUR 1191
Description: A serum-free medium that is ideal for suspension culture of insect cell lines (HighFive, SF9).

Human Apolipoprotein AI / B Free Serum Protein

abx060869-100ml 100 ml
EUR 495

Exo-Flow 2.0 Basic Kit without antibody (Streptavidin beads + reagents) - for Serum or Plasma

EXOFLOW2-BASICA-SP 30 rxn
EUR 1001

Bradford(Coomassie) Protein Assay Plus Reagents

P7201-050 450ml
EUR 188

HSA Human Serum Albumin Recombinant Protein, Lipid Free

PROTP02768-3 Regular: 50mg
EUR 471
Description: HSA Human Recombinant lipid reduced produced in Plant is a non-glycosylated, polypeptide chain containing 585 amino acids and having a molecular mass of 67 kDa.

Insect Cell Medium: Serum-Free Insect Culture Medium

ABP-MED-10002 1 liter Ask for price

Bovine serum albumin (BSA) protein (>99%, Protease-free)

BSA16-N-100 100 mg
EUR 286

Mouse Serum

abx098261-100L 100 L
EUR 129506

Mouse Serum

20-abx098261
  • EUR 1163.00
  • EUR 272.00
  • 100 ml
  • 10 ml

Mouse Serum

abx098261-5L 5 L
EUR 8833

Mouse Serum

abx098262-1ml 1 ml
EUR 1720

Rabbit control serum (non-immunized, Disease free, SPF Rabbits)

NSPF-1 1 ml
EUR 286

Rabbit control serum (non-immunized, Disease free, SPF Rabbits)

NSPF-10 10 ml
EUR 651

Rabbit control serum (non-immunized, Disease free, SPF Rabbits)

NSPF-5 5 ml
EUR 529

Purified rat serum albumin protein (RSA, >99%, globulin free)

ALBR13-N-10 10 mg
EUR 286

Human Male AB Serum (Converted from Plasma), Xeno-Free

AR1005-0100 100mL Ask for price

Bovine Serum Albumin ? Heat Shock, Protease Free, pH 7.0

7919-100
EUR 653

Bovine Serum Albumin ? Heat Shock, Protease Free, pH 7.0

7919-25
EUR 245

Bovine Serum Albumin ? Heat Shock, Protease Free, pH 7.0

7919-5
EUR 120

500 ML INSECTAGRO® DS2 SERUM-FREE/PROTEIN-FREE MEDIUM, 1X WITHOUT L-GLUTAMINE

13-402-CV 500 mL/pk
EUR 153
Description: Specialty Media; Insect Media Products

Human IgG (serum origin, purified >97%, low endotoxin, azide free)

20007-1-LE-1 1 mg
EUR 164

Bovine Serum Albumin ? Heat Shock, Protease DNASE Free, pH 7.0

7920-100
EUR 914

Bovine Serum Albumin ? Heat Shock, Protease DNASE Free, pH 7.0

7920-1000 Ask for price

Bovine Serum Albumin ? Heat Shock, Protease DNASE Free, pH 7.0

7920-25
EUR 370

Bovine Serum Albumin ? Heat Shock, Protease DNASE Free, pH 7.0

7920-5
EUR 153

Bovine Serum Albumin ? Heat Shock, Fatty Acid Free, pH 7.0

7921-100
EUR 1132

Bovine Serum Albumin ? Heat Shock, Fatty Acid Free, pH 7.0

7921-25
EUR 446

Bovine Serum Albumin ? Heat Shock, Fatty Acid Free, pH 7.0

7921-5
EUR 175

Mouse Serum Albumin

30R-3304 10 mg
EUR 187
Description: Purified native Mouse Serum Albumin

Mouse Complement Serum

32R-CM001 5 ml
EUR 435
Description: Frozen high activity mouse complement serum
Sequencing outcomes have been validated utilizing quantitative reverse transcription PCR. The knowledge confirmed that miR-30b-5p, miR-22-3p, and miR-378a-3p have been considerably deregulated in AD, with space underneath the curve (AUC) of 0.668, 0.637, and 0.718, respectively. The mixture of the three miRs gained a greater diagnostic functionality with AUC of 0.880. This discovering revealed a miR panel as potential biomarker in the peripheral blood to tell apart AD from HC.

anti streptavidin antibody

Anti-Streptavidin antibody

STJ16100613 1 mL
EUR 478

Streptavidin Antibody

abx020705-1mg 1 mg
EUR 648

Streptavidin Antibody

20-abx319856
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Streptavidin Antibody

20-abx339012
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Streptavidin Antibody

21155-05011 150 ug
EUR 217

Streptavidin Antibody

1-CSB-PA18194A0Rb
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Streptavidin. Recognizes Streptavidin from Streptomyces avidinii. This antibody is Unconjugated. Tested in the following application: ELISA

Streptavidin Antibody

1-CSB-PA332849YA01SNO
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Streptavidin. Recognizes Streptavidin from Streptomyces avidinii. This antibody is Unconjugated. Tested in the following application: ELISA

Streptavidin antibody

20R-3017 2 mL
EUR 503
Description: Rabbit polyclonal Streptavidin antibody

Streptavidin antibody

10R-1103 100 ul
EUR 316
Description: Mouse monoclonal Streptavidin antibody

Streptavidin antibody

10R-S118a 1 mg
EUR 489
Description: Mouse monoclonal Streptavidin antibody

Streptavidin antibody

10R-S118b 1 mg
EUR 457
Description: Mouse monoclonal Streptavidin antibody

Streptavidin antibody

10R-S118c 1 mg
EUR 392
Description: Mouse monoclonal Streptavidin antibody

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

Streptavidin

E61I01602 100ug
EUR 343

Streptavidin

7-06550 2mg Ask for price

Streptavidin

7-06551 10mg Ask for price

Streptavidin

7-06552 100mg Ask for price

Streptavidin

R-1100 1 mg
EUR 197.9
Description: The best epigenetics products

Streptavidin

S0902-002 2mg
EUR 223

Streptavidin

S0902-003 10mg
EUR 421

Streptavidin

SE497 5mg
EUR 224

Streptavidin

abx670356-5mg 5 mg
EUR 467

Streptavidin

RP-1531 5 mg
EUR 164

Streptavidin

STVF-50 50 ug
EUR 115

Streptavidin

STVPE-50 50 ug
EUR 115

Streptavidin

FNSA-0001 500 uL
EUR 324
Description: Streptavidin secondary antibody

Streptavidin Polyclonal Antibody

A56491 100 µg Ask for price
Description: kits suitable for this type of research

Streptavidin Polyclonal Antibody

A50712 100 µg
EUR 570.55
Description: reagents widely cited

Phosphoserine Antibody (Streptavidin)

abx448409-400ul 400 ul
EUR 592

Phosphothreonine Antibody (Streptavidin)

abx448410-400ul 400 ul
EUR 592

Phosphotyrosine Antibody (Streptavidin)

abx448430-400ul 400 ul
EUR 592

Crotonaldehyde Antibody (Streptavidin)

abx448605-100ug 100 ug
EUR 704

Crotonaldehyde Antibody (Streptavidin)

abx448623-100ug 100 ug
EUR 704

KDEL Antibody (Streptavidin)

abx448677-100ug 100 ug
EUR 606

KDEL Antibody (Streptavidin)

abx448695-100ug 100 ug
EUR 606

KDEL Antibody (Streptavidin)

abx448713-100ug 100 ug
EUR 606

GRP94 Antibody (Streptavidin)

abx448731-100ug 100 ug
EUR 606

Ubiquitin Antibody (Streptavidin)

abx448839-100ug 100 ug
EUR 662

Ubiquitin Antibody (Streptavidin)

abx448857-100ug 100 ug
EUR 662

GST Antibody (Streptavidin)

abx448875-100ug 100 ug
EUR 606

Ubiquitin Antibody (Streptavidin)

abx448893-100ug 100 ug
EUR 662

Metallothionein Antibody (Streptavidin)

abx448911-100ug 100 ug
EUR 606

Metallothionein Antibody (Streptavidin)

abx448929-100ug 100 ug
EUR 606

Metallothionein Antibody (Streptavidin)

abx448947-100ug 100 ug
EUR 606

Tbj51 Antibody (Streptavidin)

abx448983-100ug 100 ug
EUR 606

TbHsp70 Antibody (Streptavidin)

abx449001-100ug 100 ug
EUR 606

CBP Antibody (Streptavidin)

abx449073-100ug 100 ug
EUR 606

CBP Antibody (Streptavidin)

abx449091-100ug 100 ug
EUR 606

anti ctla 4 clone 9h10

Mouse Anti-Mouse CTLA-4 (CD152) Monoclonal antibody, clone 9D9

CABT-L4442-1mg 1 mg
EUR 897

Mouse Anti-Mouse CTLA-4 (CD152) Monoclonal antibody, clone 9D9

CABT-L4442-5mg 5 mg
EUR 2405

Mouse Anti-Human CTLA-4 (CD152) Monoclonal antibody, clone BN13

CABT-L4463-1mg 1 mg
EUR 897

Mouse Anti-Human CTLA-4 (CD152) Monoclonal antibody, clone BN13

CABT-L4463-5mg 5 mg
EUR 2405

Hamster Anti CTLA-4 (CD152) Antibody

20-abx137133
  • EUR 467.00
  • EUR 648.00
  • 0.5 mg
  • 1 mg

Anti-CTLA-4 (Iplimumab), Humanized Antibody

A2110-100 100 µg
EUR 510

Anti-Smac/DIABLO (mouse) Monoclonal Antibody (9H10)

M03790-1 100ug
EUR 484
Description: Rat Monoclonal Smac/DIABLO (mouse) Antibody (9H10). Validated in ELISA, IP, IF and tested in Mouse.

CD152 (CTLA-4) Antibody

abx021366-02mg 0.2 mg
EUR 1017

CTLA 4 Recombinant Protein

96-215 0.2 mg
EUR 474.5
Description: CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) is also known as CD152 (Cluster of differentiation 152), is a protein receptor that downregulates the immune system. CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. The protein contains an extracellular V domain, a transmembrane domain, and a cytoplasmic tail. Alternate splice variants, encoding different isoforms. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. Fusion proteins of CTLA4 and antibodies (CTLA4-Ig) have been used in clinical trials for rheumatoid arthritis.

CTLA 4 Recombinant Protein

96-216 0.2 mg
EUR 474.5
Description: CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) is also known as CD152 (Cluster of differentiation 152), is a protein receptor that downregulates the immune system. CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. The protein contains an extracellular V domain, a transmembrane domain, and a cytoplasmic tail. Alternate splice variants, encoding different isoforms. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. Fusion proteins of CTLA4 and antibodies (CTLA4-Ig) have been used in clinical trials for rheumatoid arthritis.

CTLA 4 Recombinant Protein

96-218 0.1 mg
EUR 364.25
Description: CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) is also known as CD152 (Cluster of differentiation 152), is a protein receptor that downregulates the immune system. CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. The protein contains an extracellular V domain, a transmembrane domain, and a cytoplasmic tail. Alternate splice variants, encoding different isoforms. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. T cell activation through the T cell receptor and CD28 leads to increased expression of CTLA-4, an inhibitory receptor for B7 molecules. Fusion proteins of CTLA4 and antibodies (CTLA4-Ig) have been used in clinical trials for rheumatoid arthritis.

CTLA 4 Recombinant Protein

96-219 0.2 mg
EUR 401
Description: CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) is also known as CD152 (Cluster of differentiation 152), is a protein receptor that downregulates the immune system. CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. The protein contains an extracellular V domain, a transmembrane domain, and a cytoplasmic tail. Alternate splice variants, encoding different isoforms. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. Fusion proteins of CTLA4 and antibodies (CTLA4-Ig) have been used in clinical trials for rheumatoid arthritis.

CTLA-4 Recombinant Protein

96-858 0.1 mg
EUR 542.75
Description: CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) is also known as CD152 (Cluster of differentiation 152), is a protein receptor that downregulates the immune system. CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. The protein contains an extracellular V domain, a transmembrane domain, and a cytoplasmic tail. Alternate splice variants, encoding different isoforms. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. Fusion proteins of CTLA4 and antibodies (CTLA4-Ig) have been used in clinical trials for rheumatoid arthritis.

CTLA-4 Recombinant Protein

96-987 0.2 mg
EUR 401
Description: CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) is also known as CD152 (Cluster of differentiation 152), is a protein receptor that downregulates the immune system. CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. The protein contains an extracellular V domain, a transmembrane domain, and a cytoplasmic tail. Alternate splice variants, encoding different isoforms. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. Fusion proteins of CTLA4 and antibodies (CTLA4-Ig) have been used in clinical trials for rheumatoid arthritis.

CTLA-4 Recombinant Protein

96-988 0.2 mg
EUR 401
Description: CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) is also known as CD152 (Cluster of differentiation 152), is a protein receptor that downregulates the immune system. CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. The protein contains an extracellular V domain, a transmembrane domain, and a cytoplasmic tail. Alternate splice variants, encoding different isoforms. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. Fusion proteins of CTLA4 and antibodies (CTLA4-Ig) have been used in clinical trials for rheumatoid arthritis.

CTLA-4 Recombinant Protein

97-033 0.1 mg
EUR 595.25
Description: CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) is also known as CD152 (Cluster of differentiation 152), is a protein receptor that downregulates the immune system. CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. The protein contains an extracellular V domain, a transmembrane domain, and a cytoplasmic tail. Alternate splice variants, encoding different isoforms. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. Fusion proteins of CTLA4 and antibodies (CTLA4-Ig) have been used in clinical trials for rheumatoid arthritis.

CTLA-4 Recombinant Protein

97-040 0.1 mg
EUR 490.25
Description: CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) is also known as CD152 (Cluster of differentiation 152), is a protein receptor that downregulates the immune system. CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. The protein contains an extracellular V domain, a transmembrane domain, and a cytoplasmic tail. Alternate splice variants, encoding different isoforms. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. Fusion proteins of CTLA4 and antibodies (CTLA4-Ig) have been used in clinical trials for rheumatoid arthritis.

CTLA 4 Recombinant Protein

RF16010-01 0.1 mg
EUR 364.25
Description: CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) is also known as CD152 (Cluster of differentiation 152), is a protein receptor that downregulates the immune system. CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. The protein contains an extracellular V domain, a transmembrane domain, and a cytoplasmic tail. Alternate splice variants, encoding different isoforms. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. T cell activation through the T cell receptor and CD28 leads to increased expression of CTLA-4, an inhibitory receptor for B7 molecules. Fusion proteins of CTLA4 and antibodies (CTLA4-Ig) have been used in clinical trials for rheumatoid arthritis.

CTLA-4 Recombinant Protein

92-722 0.05 mg
EUR 338
Description: Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. Human or mouse CTLA4 cDNA encodes 223 amino acids (aa) including a 35 aa signal sequence, a 126 aa extracellular domain (ECD) with one Ig-like V-type domain, a 21 aa transmembrane (TM) sequence, and a 41 aa cytoplasmic sequence.It is widely expressed with highest levels in lymphoid tissues. CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.

CTLA-4 Recombinant Protein

92-723 0.05 mg
EUR 338
Description: Mouse Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule. Within the ECD, Mouse CTLA-4 shares 68% aa sequence identity with human. CTLA4 is similar to the T cell costimulatory protein CD28 since both of the molecules bind to CD80 and CD86 on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found inregulatory T cells and may play an important role in their functions. T cell activation through the T cell receptor and CD28 leads to increased expression of CTLA4. Genetic variations of CTLA4 have been associated with susceptibility to systemic lupus erythematosus(SLE), Gravesdisease(GRD), Celiac disease type3(CELIAC3) and Hepatitis B virus infection(HBVinfection).

Anti-CTLA-4 (Tremelimumab), Human IgG2 Antibody

A2163-100 100 µg
EUR 510

Hamster Mono Anti-Mouse CTLA-4 (CD152) IgG

AB-11610 100 ug
EUR 347

Anti-CD152/ CTLA-4 Antibody [BNI3], Unconjugated-100ug

QAB59-100ug 100ug
EUR 200

Anti-CD152/ CTLA-4 Antibody [BNI3], APC-100Tests

QAB59-APC-100Tests 100Tests
EUR 352

Anti-CD152/ CTLA-4 Antibody [BNI3], APC-25Tests

QAB59-APC-25Tests 25Tests
EUR 157

Anti-CD152/ CTLA-4 Antibody [BNI3], PE-100Tests

QAB59-PE-100Tests 100Tests
EUR 259

Anti-CD152/ CTLA-4 Antibody [BNI3], PE-25Tests

QAB59-PE-25Tests 25Tests
EUR 149

Recombinant Human CTLA-4 Protein

RP01044 10 μg
EUR 145

CTLA-4 Fc Recombinant Protein

40-692 50 ug
EUR 259.25
Description: CTLA-4 and CD28 are receptors of the immunoglobulin superfamily that are expressed, along with the transmembrane glycoproteins B7-1 and B7-2, by antigen-presenting cells, and with these ligands constitute crucial co-stimulatory pathways for T and B cell regulatory responses. It is through engagement with CD28 and CTLA-4 that the B7 family ligands B7-1 and B7-2 play principal roles in immunity by activating immune response and maintaining immune tolerance. Co-stimulatory signals generated by B7-1 and B7-2 interactions with CD28 serve to stimulate T cell activation and prevent anergy through the amplification of T cell receptor (TCR) signaling. In contrast, interactions of the ligands with CTLA-4 serves to maintain T cell homeostasis and self-tolerance through the disruption of stimulatory signaling from B7 isoform-bound CD28 complexes, and by inducing powerful inhibitory signals in T cells. CTLA-4, like B7-1, is only poorly expressed on resting dendritic cells; therefore, up-regulation of their interaction and resultant amplification and regulation of T cell activity at peripheral inflammation sites is considerably delayed upon immune activation. Conversely, B7-2 and CD28 are constitutively expressed by resting hematopoietic and T cells, respectively, and as a result are able to rapidly induce up-regulation upon immune activation, making them critical to the early co-stimulatory signaling of immune response. Unlike B7-1 and B7-2, the ligands PD-L1 (or B7-H1) and B7-H2, which also belong to the B7 family, have not been shown to influence immunity through interaction with CTLA-4. B7-H2 has been shown to have restricted interaction with CD28. The difference in expression of B7-1, B7-2 and B7-H2 may enable temporally and spatially-specific regulation of T cell response through non-competitive CD28 interaction. CHO cell-derived Recombinant Human CTLA-4 Fc is a glycosylated, disulfide-linked homodimer of 714 amino acid residues whose monomer consists of the 124-amino-acid length extracellular portion of CTLA-4 fused to the 231-amino-acid length Fc portion of human IgG1 by two glycines. The calculated molecular weight of Recombinant Human CTLA-4 Fc dimer is 78.7 kDa; however, due to glycosylation, the monomer and dimer migrate at apparent molecular weights of approximately 45–50 kDa and 80–90 kDa by SDS-PAGE analysis under reducing conditions.

CD152 [CTLA-4] Recombinant Protein

90-411 100 ug
EUR 285.5
Description: CD152 and CD28, together with their ligands B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD152 and CD28 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. Both CD152 and CD28 are composed of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. CD152 and CD28 are both expressed on the cell surface as disulfide-linked homodimers or as monomers. CD152 was originally identified as a gene that was specifically expressed by cytotoxic T lymphocytes. However, CD152 transcripts have since been found in both Th1 and Th2, and CD4+ and CD8+ T cell clones. Whereas, CD28 expression is constitutive on the surfaces of 95% of CD4+ T cells and 50% of CD8+ T cells and is down regulated upon T cell activation, CD152 expression is upregulated rapidly following T cell activation and peaks approximately 24 hours following activation. Although both CD152 and CD28 can bind to the same ligands, CD152 binds to B71 and B72 with 20-100-fold higher affinity than CD28.

CD152 [CTLA-4] Recombinant Protein

90-412 500 ug
EUR 464
Description: CD152 and CD28, together with their ligands B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD152 and CD28 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. Both CD152 and CD28 are composed of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. CD152 and CD28 are both expressed on the cell surface as disulfide-linked homodimers or as monomers. CD152 was originally identified as a gene that was specifically expressed by cytotoxic T lymphocytes. However, CD152 transcripts have since been found in both Th1 and Th2, and CD4+ and CD8+ T cell clones. Whereas, CD28 expression is constitutive on the surfaces of 95% of CD4+ T cells and 50% of CD8+ T cells and is down regulated upon T cell activation, CD152 expression is upregulated rapidly following T cell activation and peaks approximately 24 hours following activation. Although both CD152 and CD28 can bind to the same ligands, CD152 binds to B71 and B72 with 20-100-fold higher affinity than CD28.

CD152 [CTLA-4] Recombinant Protein

90-415 100 ug
EUR 364.25
Description: CD152 [CTLA-4] and CD28, together with their ligands B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD152 and CD28 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. Both CD152 and CD28 are composed of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. CD152 and CD28 are both expressed on the cell surface as disulfide-linked homodimers or as monomers. CD152 was originally identified as a gene that was specifically expressed by cytotoxic T lymphocytes. However, CD152 transcripts have since been found in both Th1 and Th2, and CD4 + and CD8 + T cell clones. Whereas, CD28 expression is constitutive on the surfaces of 95% of CD4 + T cells and 50% of CD8 + T cells and is down regulated upon T cell activation, CD152 expression is upregulated rapidly following T cell activation and peaks approximately 24 hours following activation. Although both CD152 and CD28 can bind to the same ligands, CD152 binds to B71 and B72 with 20-100-fold higher affinity than CD28.

CD152 [CTLA-4] Recombinant Protein

90-416 100 ug
EUR 311.75
Description: CD152 and CD28, together with their ligands B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD152 and CD28 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. Both CD152 and CD28 are composed of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. CD152 and CD28 are both expressed on the cell surface as disulfide-linked homodimers or as monomers. CD152 was originally identified as a gene that was specifically expressed by cytotoxic T lymphocytes. However, CD152 transcripts have since been found in both Th1 and Th2, and CD4+ and CD8+ T cell clones. Whereas, CD28 expression is constitutive on the surfaces of 95% of CD4+ T cells and 50% of CD8+ T cells and is down regulated upon T cell activation, CD152 expression is upregulated rapidly following T cell activation and peaks approximately 24 hours following activation. Although both CD152 and CD28 can bind to the same ligands, CD152 binds to B71 and B72 with 20-100-fold higher affinity than CD28.

CD152 [CTLA-4] Recombinant Protein

90-417 500 ug
EUR 490.25
Description: CD152 and CD28, together with their ligands B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD152 and CD28 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. Both CD152 and CD28 are composed of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. CD152 and CD28 are both expressed on the cell surface as disulfide-linked homodimers or as monomers. CD152 was originally identified as a gene that was specifically expressed by cytotoxic T lymphocytes. However, CD152 transcripts have since been found in both Th1 and Th2, and CD4+ and CD8+ T cell clones. Whereas, CD28 expression is constitutive on the surfaces of 95% of CD4+ T cells and 50% of CD8+ T cells and is down regulated upon T cell activation, CD152 expression is upregulated rapidly following T cell activation and peaks approximately 24 hours following activation. Although both CD152 and CD28 can bind to the same ligands, CD152 binds to B71 and B72 with 20-100-fold higher affinity than CD28.

Anti-ACTA2 Rabbit Monoclonal Antibody, Clone#RM253

M01072-4 100ul
EUR 375
Description: Anti-ACTA2 Rabbit Monoclonal Antibody, Clone#RM253 tested in WB, IHC, reactive to Human, Mouse, (Bovine, Rat)

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

Anti-CTLA + CTLB antibody

STJ71704 100 µg
EUR 359

Anti-Histone H2A Rabbit Monoclonal Antibody, Clone#RM225

M16777-4 100ug
EUR 468
Description: Anti-Histone H2A Rabbit Monoclonal Antibody, Clone#RM225 tested in WB, ELISA, Multiplex, ICC, reactive to All Vertebrates

Anti-Cyclin B1 Rabbit Monoclonal Antibody, Clone#RM281

M00745-4 100uL
EUR 375
Description: Anti-Cyclin B1 Rabbit Monoclonal Antibody, Clone#RM281 tested in WB, IHC, reactive to Human

CTLA-4 (extracellular domain) scaffold protein anti-Human CD80

SCT-L065 1 mg
EUR 4496
Description: Scaffold protein

CTLA-4 (extracellular domain) scaffold protein anti-Human CD86

SCT-L249 1 mg
EUR 4496
Description: Scaffold protein

Anti-CD152/ CTLA-4 Antibody [BNI3], Qfluor 630-100ug

QAB59-QF630-100ug 100ug
EUR 276

Recombinant Human CTLA-4/CD152 Protein

RP00343 10 μg
EUR 145

Recombinant Mouse CTLA-4/CD152 Protein

RP00755 10 μg
EUR 145

Human CTLA 4 Soluble ELISA Kit

QY-E05452 96T
EUR 361

Anti-NeuN (Fox3, RBFOX3) Rabbit Monoclonal Antibody, Clone#RM312

M11954-4 100uL
EUR 385
Description: Anti-NeuN (Fox3, RBFOX3) Rabbit Monoclonal Antibody, Clone#RM312 tested in WB, IHC, reactive to Human

Anti-AKT (PH domain) Rabbit Monoclonal Antibody, Clone#RM316

M00024-4 100uL
EUR 385
Description: Anti-AKT (PH domain) Rabbit Monoclonal Antibody, Clone#RM316 tested in WB, IHC, reactive to Human

Anti-AR (N-terminal) Rabbit Monoclonal Antibody, Clone#RM254

M00542-4 100uL
EUR 427
Description: Anti-AR (N-terminal) Rabbit Monoclonal Antibody, Clone#RM254 tested in WB, IHC, reactive to Human

Anti-Aurora-B (AURKB) Rabbit Monoclonal Antibody, Clone#RM278

M00762-4 100uL
EUR 375
Description: Anti-Aurora-B (AURKB) Rabbit Monoclonal Antibody, Clone#RM278 tested in WB, IHC, reactive to Human

Anti-CK8 (Cytokeratin-8) Rabbit Monoclonal Antibody, Clone#RM266

M01421-4 100uL
EUR 375
Description: Anti-CK8 (Cytokeratin-8) Rabbit Monoclonal Antibody, Clone#RM266 tested in WB, IHC, reactive to Human

anti mouse pd 1 antibody

Anti-PD-1 Antibody

A1384-100
EUR 338

Anti-PD-1 Antibody

A1384-30T
EUR 146

XStamp Pro anti-PD-1 EV Targeting Kit

XSTP915A-1 10 rxn
EUR 805

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Anti-PD-1 (PDCD1) antibody

STJ180216 0.1 ml
EUR 212

anti- PD-1/CD279 antibody

FNab06234 100µg
EUR 585
Description: Antibody raised against PD-1/CD279

anti- PD-1/CD279 antibody

FNab06235 100µg
EUR 585
Description: Antibody raised against PD-1/CD279

Anti-PD-1 Biotinylated Antibody

A1996-100 100 µg
EUR 343

Anti-PD-1 Biotinylated Antibody

A1996-30 30 µg
EUR 156

Anti-PD-1/CD279 antibody

PAab06234 100 ug
EUR 412

PD 166326

C3677-1 1 mg
EUR 161
Description: IC50: 8 nM for c-abl PD 166326 is a receptor tyrosine kinase inhibitor.Receptor tyrosine kinases are the high-affinity cell surface receptors for many growth factors, cytokines, as well as hormones.

PD 198306

B7124-1 1 mg
EUR 126
Description: IC50: 8 nM for MEK [1]PD 198306 is a potent, selective and non-ATP competitive MAPK/ERK-kinase (MEK) inhibitor. MEK is a kinase enzyme which phosphorylates mitogen-activated protein kinase (MAPK).

PD 173074

1675-1
EUR 137

Anti-PD-1 (Pembrolizumab) Biotinylated Antibody

A2073-50 50 µg
EUR 379

Anti-PD-1 (Nivolumab) Biotinylated Antibody

A2117-100 100 µg
EUR 343

Anti-PD-1 (Nivolumab) Biotinylated Antibody

A2117-30T 30 µg
EUR 156

Anti-PD-1 (Spartalizumab) humanized Antibody

A2131-100 100 µg
EUR 530

Anti-PD-1 (Camrelizumab) humanized Antibody

A2132-100 100 µg
EUR 530

Anti-PD-1 (Toripalimab), Humanized Antibody

A2161-100 100 µg
EUR 510

Anti-PD-1 (Pembrolizumab), humanized Antibody

A1306-100
EUR 501

Anti-PD-1 (Nivolumab), Humanized Antibody

A1307-100
EUR 501

Mouse Anti-Human CD279 (PD-1) mAbConjugated Antibody

CCM019 100ul
EUR 397

Anti-PD-ECGF Antibody

A06329 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for PD-ECGF Antibody (TYMP) detection.tested for IHC, WB in Human.

Anti-PD-L2 antibody

STJ98748 200 µl
EUR 197
Description: Rabbit polyclonal to PD-L2.

Anti-PD-ECGF antibody

STJ96779 200 µl
EUR 197
Description: Rabbit polyclonal to PD-ECGF.

Anti-PD-L1 antibody

STJ130022 50 µl
EUR 321
Description: Programmed death-ligand 1 (PD-L1) is a 40kDa type 1 transmembrane protein that suppresses immune system. PD-L1 is expressed in hematopoietic and nonhematopoietic cells including T cells and B cells and various types of tumor cells. PD-L1 binds to its receptor Programmed death 1 (PD1). During infection or inflammation, PD1PD-L1 interaction is important for preventing autoimmunity. In tumor microenvironments, PD1-PD-L1 interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human cancers. In recent years, PDL1 has become an important biomarker and immunotherapy target for many types of malignancies.

Anti-PD-L1 antibody

STJ130023 50 µl
EUR 321
Description: Programmed death-ligand 1 (PD-L1) is a 40kDa type 1 transmembrane protein that suppresses immune system. PD-L1 is expressed in hematopoietic and nonhematopoietic cells including T cells and B cells and various types of tumor cells. PD-L1 binds to its receptor Programmed death 1 (PD1). During infection or inflammation, PD1PD-L1 interaction is important for preventing autoimmunity. In tumor microenvironments, PD1-PD-L1 interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human cancers. In recent years, PDL1 has become an important biomarker and immunotherapy target for many types of malignancies.

Anti-PD-L1 antibody

STJ130024 50 µl
EUR 321
Description: Programmed death-ligand 1 (PD-L1) is a 40kDa type 1 transmembrane protein that suppresses immune system. PD-L1 is expressed in hematopoietic and nonhematopoietic cells including T cells and B cells and various types of tumor cells. PD-L1 binds to its receptor Programmed death 1 (PD1). During infection or inflammation, PD1PD-L1 interaction is important for preventing autoimmunity. In tumor microenvironments, PD1-PD-L1 interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human cancers. In recent years, PDL1 has become an important biomarker and immunotherapy target for many types of malignancies.

Anti-PD-L1 antibody

STJ180217 0.1 ml
EUR 280

Anti-PD-L1 antibody

STJ180383 0.1 ml
EUR 246

Anti-PD-L1 antibody

STJ190082 200 µl
EUR 197
Description: Unconjugated Mouse monoclonal to PD-L1 (AS1A7)

anti- PD-ECGF antibody

FNab06264 100µg
EUR 585
Description: Antibody raised against PD-ECGF

Anti-PD-L1 Antibody

A1454-100
EUR 338

Anti-PD-L1 Antibody

A1454-30T
EUR 146

Anti-PD-ECGF antibody

PAab06264 100 ug
EUR 412

PD-1 Antibody

24505-100ul 100ul
EUR 390

PD-1 Antibody

24506-100ul 100ul
EUR 390

PD-1 Antibody

P1001-01m 0.1m
EUR 165

PD-1 Antibody

P1001-1ml 1ml
EUR 376

PD-1 Antibody

4065-002mg 0.02 mg
EUR 171.82
Description: PD-1 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases.

PD-1 Antibody

4065-01mg 0.1 mg
EUR 436.42
Description: PD-1 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases.

PD-1 Antibody

4067-002mg 0.02 mg
EUR 171.82
Description: PD-1 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases.

PD-1 Antibody

4067-01mg 0.1 mg
EUR 436.42
Description: PD-1 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases.

Anti-PD-L1 (CD274) (B7-H1) Rabbit Monoclonal Antibody, Clone#RM320

M00109-1 100uL
EUR 427
Description: Anti-PD-L1 (CD274) (B7-H1) Rabbit Monoclonal Antibody, Clone#RM320 tested in WB, IHC, reactive to Human

Mouse Anti-Human CD279 (PD-1) mAb

CM019-100ug 100ug
EUR 281

Mouse Anti-Human CD279 (PD-1) mAb

CM019-25ug 25ug
EUR 165

Mouse Anti-Human CD279 (PD-1) mAb

CM020-100ug 100ug
EUR 281

Mouse Anti-Human CD279 (PD-1) mAb

CM020-25ug 25ug
EUR 165

Mouse Anti-Human CD279 (PD-1) mAb

CM021-100ug 100ug
EUR 281

anti-his antibody

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

Rat Anti-Histones IgG-specific ELISA Kit, 96 tests, Quantitative

650-430-HIS 1 Kit
EUR 712

Anti-HIS-O2 antibody

STJ11100094 100 µl
EUR 277

Anti-His-tag antibody

STJ99289 200 µl
EUR 197
Description: Mouse monoclonal to His-tag.

Anti-His-Tag antibody

STJ96906 200 µl
EUR 197
Description: Mouse monoclonal to His-Tag.

Anti-His-Tag antibody

STJ96925 200 µl
EUR 197
Description: Mouse monoclonal to His-Tag.

Anti-His-Tag antibody

STJ97031 200 µl
EUR 197
Description: Mouse monoclonal to His-Tag.

Anti-His-Tag antibody

STJ97043 200 µl
EUR 197
Description: Mouse monoclonal to His-Tag.

Anti-His-Tag antibody

STJ97079 200 µl
EUR 197
Description: Rabbit polyclonal to His-Tag.

Histidine-tag (poly-His/Hisx6) Protein (His-tag-fusion protein) ELISA Kit, 96 tests, Quantitative

800-440-HIS 1 kit
EUR 895

anti- 6*His, His-Tag antibody

FNab00008 100µg
EUR 505.25
Description: Antibody raised against 6*His, His-Tag

anti- 6*His, His-Tag antibody

FNab00009 100µg
EUR 505.25
Description: Antibody raised against 6*His, His-Tag

anti- 6*his,His tag antibody

FNab00010 100µg
EUR 505.25
Description: Antibody raised against 6*his,His tag

Anti-6*his,His tag antibody

PAab00010 100 ug
EUR 355

Recombinant Human ACP5 Protein, His, Insect-1mg

QP10502-HIS-1mg 1mg
EUR 5251

Recombinant Mouse GSTM1 Protein, His, E.coli-25ug

QP10658-HIS-25ug 25ug
EUR 201

Recombinant Mouse GSTM1 Protein, His, E.coli-5ug

QP10658-HIS-5ug 5ug
EUR 155

Recombinant Human ACPP Protein, His, E.coli-100ug

QP10946-HIS-100ug 100ug
EUR 1261

Recombinant Human ACPP Protein, His, E.coli-10ug

QP10946-HIS-10ug 10ug
EUR 201

Recombinant Human ACPP Protein, His, E.coli-1mg

QP10946-HIS-1mg 1mg
EUR 3655

Recombinant Human ACPP Protein, His, E.coli-20ug

QP10946-HIS-20ug 20ug
EUR 201

Recombinant Human ACPP Protein, His, E.coli-2ug

QP10946-HIS-2ug 2ug
EUR 155

Recombinant Human ACPP Protein, His, E.coli-5ug

QP10946-HIS-5ug 5ug
EUR 155

Recombinant Human ADAM10 Protein, His, E.coli-10ug

QP10961-HIS