p53 pathway

IDO Pathway inhibitor
2746-50 each
EUR 144

Akt Pathway Sampler Kit
E051001 5x50ug
EUR 475
Description: Available in various conjugation types.

Akt Pathway Sampler Kit
MBS8505956-5x005mg 5x0.05mg
EUR 575

Wnt pathway activator 1
MBS133516-INQUIRE INQUIRE Ask for price

Wnt pathway inhibitor 3
HY-153750 10 mg
EUR 54.11
Description: Wnt pathway inhibitor 3 is a potent wnt inhibitor with an IC50 value of 45 nM. Wnt pathway inhibitor 3 shows antiproliferative activity[1].

Wnt pathway inhibitor 4
HY-153753 10 mg
EUR 54.11
Description: Wnt pathway inhibitor 4 (compound 16D) is an anticancer agent that has anti-proliferative activity[1].

Wnt pathway activator 2
HY-136073 10 mg
EUR 919.93
Description: Wnt pathway activator 2 is a potent Wnt activator extracted from patent WO2012024404A1, compound 2, has an EC50s of 13 nM[1].

MAPK Pathway Sampler Kit
E051017 5x50ug
EUR 475
Description: Available in various conjugation types.

NFκB Pathway Sampler Kit
E051021 5x50ug
EUR 475
Description: Available in various conjugation types.

Wnt pathway activator 1
MBS5755712-10mg 10mg
EUR 210

Wnt pathway activator 1
MBS5755712-25mg 25mg
EUR 305

Wnt pathway activator 1
MBS5755712-2mg 2mg
EUR 155

Wnt pathway activator 1
MBS5755712-50mg 50mg
EUR 435

Wnt pathway activator 1
MBS5755712-5mg 5mg
EUR 180

Wnt pathway activator 2
MBS5767862-5mg 5mg
EUR 915

Wnt pathway activator 2
MBS5767862-5x5mg 5x5mg
EUR 3970

MAPK Pathway Sampler Kit
MBS8504436-5x005mg 5x0.05mg
EUR 575

Wnt pathway activator 1
T17256-10mg 10mg Ask for price
Description: Wnt pathway activator 1

Wnt pathway activator 1
T17256-1g 1g Ask for price
Description: Wnt pathway activator 1

Wnt pathway activator 1
T17256-1mg 1mg Ask for price
Description: Wnt pathway activator 1

Wnt pathway activator 1
T17256-50mg 50mg Ask for price
Description: Wnt pathway activator 1

Wnt pathway activator 1
T17256-5mg 5mg Ask for price
Description: Wnt pathway activator 1

Wnt pathway activator 2
T13345-10mg 10mg Ask for price
Description: Wnt pathway activator 2

Wnt pathway activator 2
T13345-1g 1g Ask for price
Description: Wnt pathway activator 2

Wnt pathway activator 2
T13345-1mg 1mg Ask for price
Description: Wnt pathway activator 2

Wnt pathway activator 2
T13345-50mg 50mg Ask for price
Description: Wnt pathway activator 2

Wnt pathway activator 2
T13345-5mg 5mg Ask for price
Description: Wnt pathway activator 2

Integrin Pathway Sampler Kit
E051025 5x50ug
EUR 475
Description: Available in various conjugation types.

Integrin Pathway Sampler Kit
MBS8503104-5x005mg 5x0.05mg
EUR 575

NFkappaB Pathway Sampler Kit
MBS8503740-5x005mg 5x0.05mg
EUR 575

Human Notch Signaling Pathway
HNOT-I 1 set
EUR 657.6

Hh Signaling Pathway Antagonist
1659-1 each
EUR 216

Tissue factor pathway inhibitor
AP79938 1mg
EUR 2640

Tissue factor pathway inhibitor
AP88123 1mg
EUR 2640

Tissue factor pathway inhibitor
AP89055 1mg
EUR 2640

AP1 Reporter Kit (JNK Pathway)
60612 500 rxns.
EUR 565
Description: The AP1 Reporter Kit is designed for monitoring the activity of the JNK signaling pathway and the transcriptional activity of AP1 in cultured cells. The kit contains a transfection-ready AP1 luciferase reporter vector. This reporter contains the firefly luciferase gene under the control of multimerized AP1 responsive elements located upstream of a minimal promoter. The AP1 reporter is premixed with a constitutively-expressing Renilla (sea pansy) luciferase vector that serves as an internal control for transfection efficiency. The kit also includes a non-inducible firefly luciferase vector premixed with constitutively-expressing Renilla luciferase vector as a negative control. The non-inducible luciferase vector contains the firefly luciferase gene under the control of a minimal promoter, without any additional response elements. The negative control is critical for determining pathway-specific effects and the background luciferase activity.

AP1 Reporter Kit (JNK Pathway)
GWB-PSB7DB 500reactions Ask for price

JAK/STAT Pathway Sampler Kit
E051015 5x50ug
EUR 475
Description: Available in various conjugation types.

JAK/STAT Pathway Sampler Kit
MBS8503095-5x005mg 5x0.05mg
EUR 575

Human Calcium Regulation Pathway
HCAR-I 1 set
EUR 657.6

β -Catenin Pathway Sampler Kit
E051023 5x50ug
EUR 475
Description: Available in various conjugation types.

Phospho-AKT Pathway Sampler Kit
E051002 5x50ug
EUR 700
Description: Available in various conjugation types.

Phospho-PLC Pathway Sampler Kit
E051020 5x50ug
EUR 700
Description: Available in various conjugation types.

Phospho-AKT Pathway Sampler Kit
MBS8500044-5x005mg 5x0.05mg
EUR 800

Phospho-PLC Pathway Sampler Kit
MBS8500057-5x005mg 5x0.05mg
EUR 800

MTOR Pathway Antibody Sampler Kit
HAK21036 1 Kit Ask for price

Tissue factor pathway inhibitor 2
AP79755 1mg
EUR 2640

Tissue factor pathway inhibitor 2
AP88049 1mg
EUR 2640

Tissue factor pathway inhibitor 2
AP88141 1mg
EUR 2640

Phospho-MAPK Pathway Sampler Kit
E051018 5x50ug
EUR 700
Description: Available in various conjugation types.

Phospho-NFκB Pathway Sampler Kit
E051022 5x50ug
EUR 700
Description: Available in various conjugation types.

Phospho-MAPK Pathway Sampler Kit
MBS8501740-5x005mg 5x0.05mg
EUR 800

beta-Catenin Pathway Sampler Kit
MBS8503912-5x005mg 5x0.05mg
EUR 575

TOR Signaling Pathway Detection Set
MBS154734-1Set 1Set
EUR 1115

TOR Signaling Pathway Detection Set
MBS154734-5x1Set 5x1Set
EUR 5140

TOR Signaling Pathway Detection Set
PSI-1805 1 Set
EUR 1287.6
Description: The mammalian Target of Rapamycin (TOR, also known as mTOR) is an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle progression through its ability to integrate signals from nutrient levels and growth factors. TOR regulation is accomplished through a network of various activators and repressors. It is phosphorylated by Akt, whose activity is indirectly inhibited by the lipid phosphatase PTEN. TOR is normally associated with the regulatory proteins RAPTOR, a scaffold protein whose binding by TOR substrates is necessary for effective TOR-catalyzed phosphorylation, and GΒL, which stimulates TOR’s kinase activity towards downstream proteins. It is further regulated by the proteins Rheb, TSC1 and TSC2, which act to modulate TOR activity. The downstream targets of TOR are thought to be the ribosomal protein S6 kinases and the eukaryotic initiation factor 4E binding proteins (4EBPs) whose activation leads to increased protein translation and cell growth.;;For images please see PDF data sheet